Ketamine, known as Special K on the streets, has become a surprise weapon in the war against depression. Pharmaceutical companies are racing to develop drugs that improve upon it, or can be paired with it. NeuroRx has made progress with its drug, Cyclurad which, when paired with ketamine, has the potential to treat bipolar depression which doctors have struggled to treat successfully.You may find more information at Los Angeles Ketamine Treatment for Depression.
History of Ketamine
Ketamine was first developed in 1962 as a fast-acting anesthetic that is still used widely in operating rooms and for pain management. Beginning in the 1970s ketamine became popular as a recreational drug, known for putting users in a “K-hole,” likened to an out-of-body, near-death experience.
Due to abuses, in 1999 the U.S. Drug Enforcement Administration banned nonmedical uses for ketamine and designated it a Schedule III controlled substance.
According to an article in Bloomberg Business, around the same time, researchers at Yale, including Dennis Charney, who’s now dean of the Icahn School of Medicine at Mount Sinai, stumbled upon the drug’s promise as a mood stabilizer. “We were not thinking at the time that ketamine would be an antidepressant,” Charney says. When patients started reporting that they suddenly felt better, the scientists were surprised.
The group’s findings, published in Biological Psychiatry in 2000, were largely ignored. The study was tiny, and because of ketamine’s reputation as a party drug, scientists were reluctant to follow up. “They didn’t believe you could get better from depression in a few hours,” Charney adds. “They’d never seen that before.” Standard antidepressants such as Prozac and Wellbutrin take weeks or months to kick in. As many as 30 percent of depressed patients don’t respond to conventional antidepressants, according to the National Institute of Mental Health.
California Center for Ketamine Therapy – Ketamine Clinic
522 N Larchmont Blvd, Los Angeles, California 90004
Phone Number:(213) 444-5309